An analysis of imbalance of bargaining power - UK Essays.
Allelic imbalance analysis by high-density single-nucleotide polymorphic allele (SNP) array with whole genome amplified DNA. Kwong Kwok Wong, Yvonne T.M. Tsang, Jianhe Shen, Rita S. Cheng, Yi Mieng Chang, Tsz Kwong Man, Ching C. Lau.
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Genetic mechanisms underlying origin and progression of lung cancer are still poorly understood, despite the numerous studies which identified many genomic alterations. Using polymorphic microsatellites, allelic imbalances have been frequently found at loci such as 3p, 5q, 8p, 9p and 9q, 11p and 11q, and 17q without either histologic specificity or prognosis value.
Here we assessed allelic imbalance (AI) in the heterozygote state of rice under non- and water-stress treatments and determined association of asymmetrically expressed genes with grain yield (GY) under drought stress by in-silico co-localization analysis and selective genotyping.
Allelic imbalance (AI) is defined as the decrease of the ratios between the expressions from the variant allele and the corresponding wild-type one. AI of gene expression is common in humans and is of interest because of its potential contribution to variation in heritable traits.
Abstract We have determined regions of allelic imbalance in human breast cancer cells using highly polymorphic microsatellite markers, which can be rapidly typed by the polymerase chain reaction (PCR) using very small amounts of DNA.
In conclusion this assignment has discussed the issues of power and how social workers need to be sensitive to and recognise power imbalances. .Following this, risk discourse has been explained, as well as a task centred approach to the case study.
Recent genome-wide association studies have identified novel loci associated with coronary heart disease (CHD). One locus identified through the large-scale Coronary ARtery DIsease Genome wide Repl.
Allele-specific measurements of transcription factor binding from ChIP-seq data are key to dissecting the allelic effects of non-coding variants and their contribution to phenotypic diversity. However, most methods of detecting an allelic imbalance assume diploid genomes.
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Abstract. To study genetic changes associated with the development of breast cancer and the extent of its hereditary predisposition, paraffin-embedded tissue samples were obtained.
Allelic expression imbalance analysis compares allelic expression within individuals (in heterozygotes) and, in principle, eliminates the effect of trans-acting and nongenetic factors. Thus, compared with total transcript-based analysis (performed across individuals), the AEI analysis provides higher sensitivity to uncover cis-regulatory elements ( 26 ).
The chicken polydactyly (Po) locus causes allelic imbalance and ectopic expression of Shh during limb development Ian C. Dunn Division of Genetics and Genomics, The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, United Kingdom.
